In recent years, numerous risk factors for solid tumors have been identified. The focus here is on genetic changes that are hereditary and, according to current projections, are responsible for around one third of breast and colorectal cancer. These can be tested using multigene tests, which are now readily available in many EU countries. However, the interpretation of genetic information on risk prediction and clinical prediction programs based on it have not yet been sufficiently scientifically evaluated. It is still unclear whether risk-adjusted preventive measures actually reduce the mortality rate and to what extent they have a positive effect on the quality of life of those affected.
This discrepancy between the diagnostic offer and the evidence of clinical measures based on it requires new concepts. Since 2015, the international expert group on risk-adjusted prevention RiskAP has therefore been dealing intensely with the medical, ethical and legal challenges of genetic testing. The interdisciplinary project, funded by the German Federal Ministry of Health (BMG), aims to develop a conceptual framework and set international standards that address the manifold challenges in the field of early detection and prevention of hereditary tumors using breast cancer as an example.
At the conference, the group will present its findings and recommendations to the public and engage in discussion. The conference will be held in English.
Opening and Thematic Setup
New Knowledge in Prediction and Prevention: State of the Art
Non-Genetic Risk Factors
Prediction Based on Risk Factors
Integrating New Knowledge into the Health System:
Improving Screening and Prevention
The Concept of RiskAP
Public Health and the European Perspective
Ethical Potentials and Challenges
Prerequisites for the Improvement of Predictive Care
The Patient Perspective
Legal and Social Aspects: Genetic Diagnostics, Privacy, and Health Care System Integration
Risk Literacy: How to Inform about Risks and Empower Patients?
Panel with all Speakers
End of Meeting
Date: November 6th, 2019
Time: 11:00 am – 4:00 pm
Location: Kalkscheune Berlin, Johannisstr. 2, D-10117 Berlin, Germany
Marion Rütten, M.A.
ceres – Cologne Center for Ethics, Rights, Economics, and Social Sciences of Health
+49 (0)221 - 470 89101
ceres-sekretariat [at] uni-koeln.de